麻醉品依赖的动物与人类关联：简要综述
Animal-human correlates of narcotic dependence: a brief review.
作者信息
Stimmel B, Glick S D
出版信息
Am J Psychiatry. 1978 Jul;135(7):821-5. doi: 10.1176/ajp.135.7.821.
PMID:96703
Abstract
Knowledge of opiate action in laboratory animals can be of great value in developing a rational clinical approach to the treatment of narcotic dependence. Physiological alterations experimentally produced by narcotics have been confirmed in human subjects, and classical laboratory effects of conditioning and operant behavior also have clinical counterparts. Realization of animal-human correlates of narcotic dependence allows a better understanding of the strengths and weaknesses of existing therapeutic modalities.
摘要
了解阿片类药物在实验动物中的作用，对于制定合理的临床方法来治疗麻醉品依赖具有重要价值。麻醉品在实验中产生的生理改变已在人体受试者中得到证实，而经典的条件反射和操作性行为的实验室效应在临床中也有对应情况。认识到麻醉品依赖在动物和人类中的相关性，有助于更好地理解现有治疗方式的优缺点。
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