Di Mattia D G, Lemma M, Scrofani R, Mangini A, Fundarò P
Dipartimento di Chirurgia Toracica e Cardiovascolare Ospedale Luigi Sacco, Milano.
G Ital Cardiol. 1998 Jun;28(6):630-5.
In this study are considered the short-middle term results of anterior mitral leaflet prolapse repair obtained by means of a personal operative technique: chordal shortening and free edge remodeling. In our institution since 1993 34 consecutive patients with degenerative myxomatous mitral regurgitation, (mean age 63.3 years, range 25 to 83 years), underwent surgery. Before the operation 22 patients (64.7%) were in NYHA functional class III or IV. Mitral insufficiency, evaluated by echocardiogram, was severe in all patients; a prolapse of only anterior leaflet was present in 10 patients, both leaflets prolapsed in the others. Patients with chordal rupture of anterior mitral leaflet were excluded. Anterior mitral leaflet prolapse repair was performed with two continuous sutures including the free edge as well as the chordae for a variable length (2 mm up to 5 mm) depending on the degree of the elongation. A concomitant posterior leaflet quadrangular resection was performed in 24 patients (70.5%), and the procedure was almost always completed by a posterior suture annuloplasty reinforced by a glutaraldehyde-tanned strip of autologous pericardium. There were no perioperative deaths. The postoperative course was uneventful in all cases, and there were no hospital deaths. Postoperative echocardiographic evaluation showed satisfactory valve function. The mean valvular regurgitation before surgical procedure was 3.67 +/- 0.4, after repair 0.30 +/- 0.5 (p < 0.01). Follow-up was completed in all patients (mean 16.5 months) with no late deaths. One patient required early reoperation for recurrent mitral regurgitation resulting for a recurring anterior leaflet prolapse. We conclude that this technique is a safe, effective and easy procedure for the repair of anterior mitral leaflet prolapse without rupture. Nevertheless, a larger number of patients and a longer follow-up are required to confirm our results.
本研究探讨了采用一种个人手术技术——腱索缩短和游离缘重塑术——修复二尖瓣前叶脱垂的中短期效果。自1993年起,我院连续34例退行性黏液样二尖瓣反流患者(平均年龄63.3岁,范围25至83岁)接受了手术。术前,22例患者(64.7%)处于纽约心脏协会(NYHA)心功能Ⅲ或Ⅳ级。经超声心动图评估,所有患者均存在严重二尖瓣关闭不全;10例患者仅前叶脱垂,其余患者为双叶脱垂。二尖瓣前叶腱索断裂的患者被排除。采用两根连续缝线进行二尖瓣前叶脱垂修复,缝线包括游离缘以及长度可变(2毫米至5毫米)的腱索,具体长度取决于伸长程度。24例患者(70.5%)同时进行了后叶四边形切除术,该手术几乎总是通过用戊二醛处理的自体心包条带加固的后瓣环缝合成形术完成。围手术期无死亡病例。所有病例术后病程平稳,无医院死亡病例。术后超声心动图评估显示瓣膜功能良好。手术前平均瓣膜反流为3.67±0.4,修复后为0.30±0.5(p<0.01)。所有患者均完成随访(平均16.5个月),无晚期死亡病例。1例患者因复发性二尖瓣反流导致前叶再次脱垂而需要早期再次手术。我们得出结论,该技术是一种安全、有效且简便的修复未破裂二尖瓣前叶脱垂的方法。然而,需要更多患者和更长时间的随访来证实我们的结果。