Harris F, Phoenix D A
University of Central Lancashire, Department of Applied Biology, Preston, UK.
Membr Cell Biol. 1998;11(5):591-6.
The Escherichia coli low molecular mass penicillin-binding proteins are enzymes associated with the periplasmic face of the inner membrane. This mini review discusses the membrane anchoring of these enzymes and their possible participation in a putative membrane bound protein complex involved in the regulation of peptidoglycan biosynthesis. The identification of such a complex may lead to the identification of new sites of action for antibacterial compounds.
大肠杆菌低分子量青霉素结合蛋白是与内膜周质面相关的酶。这篇小型综述讨论了这些酶的膜锚定作用以及它们可能参与的一种假定的膜结合蛋白复合物，该复合物涉及肽聚糖生物合成的调控。鉴定这样一种复合物可能会导致发现抗菌化合物的新作用位点。
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