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从患有大肠埃希氏菌性乳腺炎的母猪乳汁中分离出的大肠杆菌的毒力决定因素。

Virulence determinants of Escherichia coli isolated from milk of sows with coliform mastitis.

作者信息

Mörner A P, Faris A, Krovacek K

机构信息

Swedish University of Agricultural Sciences, Department of Obstetrics and Gynaecology, Uppsala, Sweden.

出版信息

Zentralbl Veterinarmed B. 1998 Jun;45(5):287-95. doi: 10.1111/j.1439-0450.1998.tb00796.x.

Abstract

Escherichia coli isolates recovered from the milk of sows with coliform mastitis were examined to determine their biochemical and serologic characteristics, serum resistance and ability to adhere to fibronectin and bovine fetal fibroblasts. No common biotype was identified, and a variety of serovars were detected. Ninety-five per cent of the investigated strains were serum resistant in swine serum. Binding to fibronectin was demonstrated in most of the strains. At a binding level above 13% of the added fibronectin the strains also adhered to fibroblasts. The results of the study indicate a galactogenous route of infection. The importance of the identified virulence factors need to further elucidated.

摘要

对从患有大肠埃希氏菌性乳腺炎的母猪乳汁中分离出的大肠杆菌菌株进行检测,以确定其生化和血清学特征、血清抗性以及黏附纤连蛋白和牛胎儿成纤维细胞的能力。未鉴定出常见的生物型,检测到多种血清型。95%的被调查菌株对猪血清具有血清抗性。大多数菌株都表现出与纤连蛋白结合。当结合水平高于添加纤连蛋白的13%时,这些菌株也能黏附于成纤维细胞。研究结果表明存在经乳汁感染的途径。所鉴定的毒力因子的重要性有待进一步阐明。

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