Aroch I, Ohad D G, Baneth G
Department of Clinical Science, Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel.
J Small Anim Pract. 1998 Jun;39(6):299-302. doi: 10.1111/j.1748-5827.1998.tb03655.x.
A severely hypocalcaemic, hypomagnesaemic lactating bitch exhibited clinical signs of pulmonary oedema, paresis, dementia, gastrointestinal ileus and urinary bladder atony. The total calcium, ionised calcium and magnesium levels were extremely low. The clinical picture was very different from the one typically encountered in canine lactation tetany, and instead resembled bovine postparturient paresis. Muscle tremors, rigidity and seizures were not part of the acute clinical picture, but rather atony, weakness and paresis. General muscle dysfunction probably resulted from the extremely low ionised calcium levels in combination with very low levels of magnesium and possibly potassium. Heart failure and atony of the urinary bladder and intestines were probably a result of the severe hypocalcaemia. The alteration in calcium to magnesium ratio may have depressed neuromuscular transmission, leading to paresis and atony. The unusual electrocardiogram possibly also resulted from abnormal magnesium and calcium cation levels.
一只严重低钙血症、低镁血症的哺乳母犬出现了肺水肿、轻瘫、痴呆、胃肠麻痹和膀胱肌无力的临床症状。总钙、离子钙和镁水平极低。临床症状与犬泌乳搐搦中常见的症状截然不同，反而类似于牛产后轻瘫。肌肉震颤、僵硬和癫痫发作并非急性临床症状的一部分，而是以肌无力、虚弱和轻瘫为主。全身肌肉功能障碍可能是由于极低的离子钙水平，再加上极低的镁水平以及可能的钾水平共同导致的。心力衰竭以及膀胱和肠道的肌无力可能是严重低钙血症的结果。钙镁比例的改变可能抑制了神经肌肉传递，导致轻瘫和肌无力。异常的心电图可能也是由异常的镁和钙阳离子水平引起的。
