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[圈养种群中非典型妇科宫颈涂片的演变]

[Evolution of atypical gynecological cervical smears in a captive population].

作者信息

Vilches K, Escalona A

机构信息

Departamento de Anatomía Patológica, Hospital Clínico FUSAT, Rancagua, Chile.

出版信息

Rev Med Chil. 1998 Mar;126(3):296-301.

PMID:9674300
Abstract

BACKGROUND

An atypical cervical smear may represent a wide variety of lesions, from banal diseases to invasive neoplastic lesions.

AIM

To study the evolution of atypical cervical smears in a highly controlled women population.

MATERIAL AND METHODS

A retrospective analysis of 117 women with atypical cervical smears, diagnosed between 1985 and 1994, was performed at the institutional hospital of a mining corporation in Chile.

RESULTS

Patients age ranged from 25 to 65 years. Six percent of atypical cervical smears were associated to Papillomavirus infection and 25% to unspecific infectious agents. In the second smear, during follow up, 22.2% of women had some degree of squamous intraepithelial lesion or signs of Papillomavirus infection. A cervical biopsy was performed to 69 women, confirming the presence of a squamous intraepithelial neoplasia or signs of Papillomavirus infection in 38.4% of them. Only one patient had microinvasion.

CONCLUSIONS

All patients with atypical gynecological cervical smears should be closely followed to ascertain the diagnosis.

摘要

背景

非典型宫颈涂片可能代表多种病变,从普通疾病到浸润性肿瘤病变。

目的

研究在高度受控的女性人群中非典型宫颈涂片的演变情况。

材料与方法

对1985年至1994年间在智利一家矿业公司的机构医院诊断出的117例非典型宫颈涂片患者进行回顾性分析。

结果

患者年龄在25至65岁之间。6%的非典型宫颈涂片与乳头瘤病毒感染有关,25%与非特异性感染因子有关。在随访期间的第二次涂片检查中,22.2%的女性有某种程度的鳞状上皮内病变或乳头瘤病毒感染迹象。对69名女性进行了宫颈活检,其中38.4%证实存在鳞状上皮内瘤变或乳头瘤病毒感染迹象。只有一名患者有微浸润。

结论

所有非典型妇科宫颈涂片患者都应密切随访以明确诊断。

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