Vilches K, Escalona A
Departamento de Anatomía Patológica, Hospital Clínico FUSAT, Rancagua, Chile.
Rev Med Chil. 1998 Mar;126(3):296-301.
An atypical cervical smear may represent a wide variety of lesions, from banal diseases to invasive neoplastic lesions.
To study the evolution of atypical cervical smears in a highly controlled women population.
A retrospective analysis of 117 women with atypical cervical smears, diagnosed between 1985 and 1994, was performed at the institutional hospital of a mining corporation in Chile.
Patients age ranged from 25 to 65 years. Six percent of atypical cervical smears were associated to Papillomavirus infection and 25% to unspecific infectious agents. In the second smear, during follow up, 22.2% of women had some degree of squamous intraepithelial lesion or signs of Papillomavirus infection. A cervical biopsy was performed to 69 women, confirming the presence of a squamous intraepithelial neoplasia or signs of Papillomavirus infection in 38.4% of them. Only one patient had microinvasion.
All patients with atypical gynecological cervical smears should be closely followed to ascertain the diagnosis.
非典型宫颈涂片可能代表多种病变,从普通疾病到浸润性肿瘤病变。
研究在高度受控的女性人群中非典型宫颈涂片的演变情况。
对1985年至1994年间在智利一家矿业公司的机构医院诊断出的117例非典型宫颈涂片患者进行回顾性分析。
患者年龄在25至65岁之间。6%的非典型宫颈涂片与乳头瘤病毒感染有关,25%与非特异性感染因子有关。在随访期间的第二次涂片检查中,22.2%的女性有某种程度的鳞状上皮内病变或乳头瘤病毒感染迹象。对69名女性进行了宫颈活检,其中38.4%证实存在鳞状上皮内瘤变或乳头瘤病毒感染迹象。只有一名患者有微浸润。
所有非典型妇科宫颈涂片患者都应密切随访以明确诊断。