Lu Y M, Hutton W C, Gharpuray V M
Department of Bioengineering, Clemson University, SC 29634, USA.
J Biomech Eng. 1998 Feb;120(1):48-54. doi: 10.1115/1.2834306.
A viscoelastic finite element model of a L2-L3 motion segment was constructed and used to study: (1) the behavior of the intervertebral disc with different amounts of nucleus fluid loss; and (2) the effect of different rates of fluid loss on the viscoelastic behavior of the disc. The results indicate that: (1) The viscoelastic behavior of the intervertebral disc depends to a large extent on the rate of fluid loss from the disc; the intrinsic properties of disc tissue play a role only at the early stage of compressive loading; (2) the axial strain increases, whereas the intradiscal pressure and the posterior radial disc bulge decrease with increasing fluid loss; (3) a decreasing fluid loss rate with a total fluid loss of 10 to 20 percent (from the nucleus) during the first hour of compressive loading best predicts the overall viscoelastic behavior of a disc.
构建了一个L2-L3运动节段的粘弹性有限元模型，并用于研究：（1）不同髓核液体流失量时椎间盘的行为；以及（2）不同液体流失速率对椎间盘粘弹性行为的影响。结果表明：（1）椎间盘的粘弹性行为在很大程度上取决于椎间盘的液体流失速率；椎间盘组织的固有特性仅在压缩加载的早期起作用；（2）随着液体流失增加，轴向应变增加，而椎间盘内压力和椎间盘后径向膨出减小；（3）在压缩加载的第一小时内，液体流失速率降低且总液体流失量为（来自髓核的）10%至20%时，最能预测椎间盘的整体粘弹性行为。
