Malignant mixed mullerian tumours of the body of the uterus: a clinicopathological study of 20 cases.

OBJECTIVE

To review the clinical and histopathological data on malignant mixed mullerian tumours.

DESIGN

A retrospective study of 20 cases of malignant mixed mullerian tumours seen over a period of five and half years.

SETTING

Departments of Obstetrics and Gynaecology and Anatomical Pathology at Garankuwa Acdemic Hospital.

SUBJECTS

Clinical and histopathological records of patients with malignant mixed mullerian tumours of the body of the uterus.

METHODS

Clinical record and histopathological slides were reviewed. Age, clinical presentation and histological appearances of the cases were noted.

RESULTS

The patient age ranged from 16 to 78 years with a median of 63 years (Q1 = 58.5, Q3 = 71.5). Of the 20 cases 14 died within 12 months of diagnosis. Clinical staging and histological staging had no effect on tumour behaviour and outcome of disease.

CONCLUSION

Malignant mixed mullerian tumours are predominantly seen in post menopausal women. These tumours have a very poor prognosis irrespective of clinical stage, histological grade or the type of the stroma.