DL-乙硫氨酸对小鼠肝脏转运核糖核酸碱基组成的影响。
Effects of DL-ethionine on mouse liver tRNA base composition.
作者信息
Lu L W, Chiang G H, Randerath K
出版信息
Nucleic Acids Res. 1976 Sep;3(9):2243-53. doi: 10.1093/nar/3.9.2243.
Abstract
Treatment of mice with DL-ethionine and adenine causes a reduction of all methylated bases of liver tRNA. This effect is dose-dependent and specific for the methylated bases. Individual methylated components are affected to different extents, m22G being most sensitive to inhibition.
摘要
用DL-乙硫氨酸和腺嘌呤处理小鼠会导致肝脏tRNA所有甲基化碱基减少。这种效应具有剂量依赖性且对甲基化碱基具有特异性。各个甲基化成分受到的影响程度不同，m22G对抑制最为敏感。
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