一种来自双色高粱的新型光系统II电子传递抑制剂。

A new photosystem II electron transfer inhibitor from Sorghum bicolor.

作者信息

Rimando A M, Dayan F E, Czarnota M A, Weston L A, Duke S O

机构信息

USDA-ARS-NPURU, P.O. Box 8048, University, Mississippi 38677, USA.

出版信息

J Nat Prod. 1998 Jul;61(7):927-30. doi: 10.1021/np9800708.

DOI:10.1021/np9800708

PMID:9677276

Abstract

Our study of the mechanism(s) by which sorgoleone (1) acts as a photosystem II (PS II) inhibitor led to the isolation of a new benzoquinone derivative, 2-hydroxy-5-ethoxy-3-[(Z,Z)-8',11', 14'-pentadecatriene]-rho-benzoquinone (2), from the root exudate of sorghum. The structure of 2, which is being given the name 5-ethoxy-sorgoleone, was determined by spectroscopic means. A methoxy derivative (3) of 1 was also prepared. Both 2 and 3 caused a reduction in oxygen evolution by thylakoid membranes and induced variable chlorophyll fluorescence. These compounds, however, were less active inhibitors of PS II than 1.

摘要

我们对高粱醌（1）作为光系统II（PS II）抑制剂的作用机制进行了研究，从高粱根分泌物中分离出一种新的苯醌衍生物，即2-羟基-5-乙氧基-3-[(Z,Z)-8',11',14'-十五碳三烯]-ρ-苯醌（2）。通过光谱手段确定了2的结构，它被命名为5-乙氧基高粱醌。还制备了1的甲氧基衍生物（3）。2和3都导致类囊体膜放氧量降低，并诱导叶绿素可变荧光。然而，这些化合物作为PS II抑制剂的活性比1低。