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采用电化学发光检测的罗氏电化学发光免疫分析系统

Elecsys immunoassay systems using electrochemiluminescence detection.

作者信息

Erler K

机构信息

Boehringer Mannheim GmbH, Tutzing, Germany.

出版信息

Wien Klin Wochenschr. 1998;110 Suppl 3:5-10.

PMID:9677667
Abstract

Electrochemiluminescence (ECL1) has recently been applied as detection technology for immunoassay systems from Boehringer Mannheim. In particular, the combination of ECL with universally coated micro particle technologies results in fast assays with very high sensitivity and broad measuring range. This is achieved by optimised selection of the electrochemically active "substrates" (Ruthenium chelates and tris-propylamine, TPA). Advantages of this novel application are discussed and the Elecsys 2010 system is described, which is a full automated analyser with full random access capabilities and suitable for the full immunoassay menue. In addition it features an innovative reagent information transfer technique, fast STAT function and continuous sample loading.

摘要

电化学发光(ECL1)最近已被用作勃林格曼海姆免疫分析系统的检测技术。特别是,ECL与通用包被微粒技术相结合,可实现快速检测,具有非常高的灵敏度和宽广的测量范围。这是通过优化选择电化学活性“底物”(钌螯合物和三丙胺,TPA)来实现的。本文讨论了这种新应用的优点,并描述了Elecsys 2010系统,它是一种具有完全随机存取功能的全自动分析仪,适用于全套免疫分析菜单。此外,它还具有创新的试剂信息传输技术、快速急诊功能和连续进样功能。

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