蛙肾上腺嗜铬细胞中Syntaxin和SNAP - 25的免疫组织化学显示
Immunohistochemical demonstration of syntaxin and SNAP-25 in chromaffin cells of the frog adrenal gland.
作者信息
Quintanar J L, Salinas E, Reig J A
机构信息
Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, México.
出版信息
Gen Comp Endocrinol. 1998 Aug;111(2):119-22. doi: 10.1006/gcen.1998.7110.
The release of catecholamines from chromaffin cells involves specific proteins such as synaptobrevin present in the secretory vesicles as well as syntaxin and synaptosomal-associated protein of 25 kDa (SNAP-25), both present in the plasma membrane. We have found syntaxin and SNAP-25 in chromaffin cells of the frog adrenal gland by immunohistochemistry. This result suggests that the secretion of catecholamines from chromaffin cells involves these proteins in the frog.
嗜铬细胞中儿茶酚胺的释放涉及特定蛋白质，如存在于分泌囊泡中的突触小泡蛋白，以及存在于质膜中的 syntaxin 和 25 kDa 的突触体相关蛋白（SNAP-25）。我们通过免疫组织化学在青蛙肾上腺的嗜铬细胞中发现了 syntaxin 和 SNAP-25。这一结果表明，青蛙嗜铬细胞中儿茶酚胺的分泌涉及这些蛋白质。
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