Yettram A L, Beecham M C
Department of Mechanical Engineering, Brunel University, Middlesex, England.
Med Eng Phys. 1998 Mar;20(2):103-8. doi: 10.1016/s1350-4533(98)00009-5.
The myocardium of the left ventricle of the heart is a fibrous structure, the fibres being wound helically anticlockwise on the epicardium and changing progressively through the wall thickness to being wound helically clockwise on the endocardium. At any point, therefore, the material can be considered as transversely isotropic. For mechanically modelling the ventricle, two independent material properties, the along-fibre and across-fibre moduli of elasticity are required. This paper describes a computer method for determining these by using a finite element model and matching cavity volume and ventricle length against values derived from cineangiographic and pressure data. The method is applied to a group of patients with various cardiac diagnoses and the modular ratios for their myocardia are derived.
心脏左心室的心肌是一种纤维结构，纤维在心外膜上逆时针螺旋缠绕，并在整个壁厚中逐渐变化，在内膜上顺时针螺旋缠绕。因此，在任何一点上，材料都可被视为横向各向同性。为了对心室进行力学建模，需要两个独立的材料属性，即沿纤维和跨纤维的弹性模量。本文描述了一种计算机方法，通过使用有限元模型并将腔室容积和心室长度与从电影血管造影和压力数据得出的值进行匹配来确定这些属性。该方法应用于一组患有各种心脏疾病的患者，并得出了他们心肌的模量比。
