Kirby L, Lehmann P, Majeed A
Popul Trends. 1998 Summer(92):23-8.
This study examines trends in death rates from dementias and neurodegenerative disorders in people aged 65 and over in England and Wales between 1979 and 1996. In total, there were 171,590 deaths from dementias and neurodegenerative disorders, with the number of deaths per year increasing from 3,021 in 1979 to 10,415 in 1996. Age-standardised death rates for all diagnoses combined increased from 39 to 96 per 100,000 for men and from 45 to 101 for women between 1979 and 1996. The most dramatic increase was seen in death rates from Alzheimer's disease which increased from less than 1 per 100,000 in 1979 to 19 for men and 21 for women in 1996.
本研究调查了1979年至1996年间英格兰和威尔士65岁及以上人群中痴呆症和神经退行性疾病的死亡率趋势。痴呆症和神经退行性疾病导致的死亡总数为171,590例,每年的死亡人数从1979年的3,021例增加到1996年的10,415例。1979年至1996年间,所有诊断合并的年龄标准化死亡率男性从每10万人39例增至96例,女性从45例增至101例。阿尔茨海默病死亡率的增长最为显著,从1979年的每10万人不到1例增至1996年男性的19例和女性的21例。