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[孕期及新生儿期的血铅水平。对巴里人群的研究] (注:原文中“th the newborn period”表述有误,可能是“during the newborn period”)

[Blood lead levels during pregnancy in th the newborn period. Study of the population of Bari].

作者信息

Carbone R, Laforgia N, Crollo E, Mautone A, Iolascon A

机构信息

Dipartimento di Biomedicina dell'Età Evolutiva, Università degli Studi, Bari.

出版信息

Ann Ist Super Sanita. 1998;34(1):117-9.

PMID:9679349
Abstract

Blood lead levels during pregnancy and in neonates immediately after birth have been evaluated, showing higher values in mothers compared to neonates (5.81 +/- 3.05 vs 4.87 +/- 3.60 micrograms/100 ml) and a positive correlation between maternal and neonatal levels (r = 0.82). On the basis of the results derived from the population examined, it has been observed that 6% of newborns have blood lead levels higher than 10 micrograms/100 ml a value recently identified by the Centers for Disease Control (CDC, Atlanta, USA) as a limit for toxicity in children. Moreover, neonatal Pb levels were higher than those found in infants from 6 to 12 months (4.87 +/- 3.60 vs 2.24 +/- 0.54 micrograms/100 ml). During the first week of life there is a steady decrease of blood lead levels, together with increasing renal lead excretion. This study was carried out at the "Dipartimento di Biomedicina dell'Età Evolutiva" University of Bari, southern Italy.

摘要

研究评估了孕期及新生儿出生后即刻的血铅水平,结果显示母亲的血铅水平高于新生儿(分别为5.81±3.05微克/100毫升和4.87±3.60微克/100毫升),且母亲与新生儿的血铅水平呈正相关(r = 0.82)。根据所检测人群的结果发现,6%的新生儿血铅水平高于10微克/100毫升,这一数值最近被美国亚特兰大疾病控制中心(CDC)确定为儿童中毒的限值。此外,新生儿的血铅水平高于6至12个月婴儿的血铅水平(分别为4.87±3.60微克/100毫升和2.24±0.54微克/100毫升)。在出生后的第一周内,血铅水平持续下降,同时肾脏铅排泄增加。本研究在意大利南部巴里大学的“进化生物学系”开展。

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