Kazumori H, Sizuku T, Uchida Y, Moritani M, Yamamoto S
Dept. of Internal Medicine, Hirata Municipal Hospital.
Gan To Kagaku Ryoho. 1998 Jul;25(8):1213-6.
A 73-year-old man complaining of general fatigue and abdominal fullness was hospitalized in April 1994. Hepatocellular carcinoma (HCC) measuring 25 x 11 cm was detected in the right liver lobe. The patient received transcatheter artery embolization, and AFP and PIVKA-II levels were decreased thereafter. However, after three months, AFP levels were increased gradually. Therefore, 300 mg of UFT was administered daily. AFP and PIVKA-II levels decreased and the tumor decreased in size. The patient remained in a good state of health for about two years and six months. Our case suggests that UFT is effective for the treatment of HCC.
一名73岁男性因全身乏力和腹部饱胀感于1994年4月住院。在右肝叶发现了一个大小为25×11厘米的肝细胞癌(HCC)。患者接受了经动脉导管栓塞术,此后甲胎蛋白(AFP)和异常凝血酶原(PIVKA-II)水平下降。然而,三个月后,AFP水平逐渐升高。因此,每天给予300毫克优福定(UFT)。AFP和PIVKA-II水平下降,肿瘤体积缩小。患者保持了约两年零六个月的良好健康状态。我们的病例表明,优福定对肝细胞癌的治疗有效。