Stamatopoulos K, Kanellopoulou G, Vaiopoulos G, Stamatellos G, Yataganas X
First Department of Medicine, University of Athens School of Medicine, Laikon General Hospital, Greece.
Leuk Res. 1998 Aug;22(8):759-61. doi: 10.1016/s0145-2126(98)00008-3.
Cytarabine therapy is rarely complicated by cardiotoxicity. The present report describes the clinical course of a 35-year-old female patient with acute myelogenous leukemia in complete remission, who developed sinus bradycardia while on high dose cytarabine as a consolidation therapy. The electrocardiographic findings suggested that bradycardia was most probably the result of sinoatrial blockade. The available information regarding a possible association of cytarabine with disturbances of cardiac rhythm is reviewed.
