Kohlhase B, Kececioglu D, Nowak-Göttl U
Department of Pediatric Cardiology, University Children's Hospital, Münster, Germany.
Cardiol Young. 1998 Jan;8(1):116-8. doi: 10.1017/s1047951100004741.
Formation of thrombus in the heart is a rare event in children. Genetic risk factors determined for thrombophilia with additional exogenous risk factors may, none the less, promote cardiac thrombosis. We report on a boy without predisposing cardiac disease, heterozygous for resistance to activated protein C, who developed multiple thrombuses attached to the mitral valve which led to recurrent arterial thromboembolism. In addition this patient showed enhanced levels of lipoprotein (a).
心脏血栓形成在儿童中是一种罕见事件。尽管确定的遗传性血栓形成倾向风险因素与额外的外源性风险因素可能会促进心脏血栓形成。我们报告了一名没有易患心脏病的男孩，他对活化蛋白C有抵抗，呈杂合子状态，其二尖瓣上形成了多个血栓，导致反复发生动脉血栓栓塞。此外，该患者的脂蛋白(a)水平升高。
