Patel K, Carrington P A, Bhatnagar S, Houghton J B, Routledge R C
Department of Medicine, Jamaica Hospital Medical Center, New York, USA.
Clin Lab Haematol. 1998 Feb;20(1):53-5. doi: 10.1046/j.1365-2257.1998.00085.x.
Extramedullary cutaneous plasmacytoma is an uncommon observation in clinical practice. In most of the cases it is usually an extension of underlying medullary plasmacytoma. This case report describes a patient with IgD myeloma who went into plateau phase following standard intravenous chemotherapy. After more than a year in plateau phase, he developed multiple fleshy nodular lesions in the skin. Biopsy of one of the lesions revealed relapse of myeloma in the skin. His IgD paraprotein remained in plateau phase and the bone marrow showed only 1% plasma cells. The patient has been treated with systemic intravenous chemotherapy followed by local radiotherapy.
髓外皮肤浆细胞瘤在临床实践中较为罕见。多数情况下，它通常是潜在髓质浆细胞瘤的扩展。本病例报告描述了一名患有IgD骨髓瘤的患者，在接受标准静脉化疗后进入平台期。在平台期超过一年后，他的皮肤出现了多个肉质结节性病变。其中一个病变的活检显示皮肤骨髓瘤复发。他的IgD副蛋白仍处于平台期，骨髓中仅显示1%的浆细胞。该患者接受了全身静脉化疗，随后进行了局部放疗。
