Theodorou K, Kappas C, Tsokas C
Medical Physics Department, Medical School, University of Patras, Hellas, Greece.
Radiother Oncol. 1998 Jun;47(3):313-7. doi: 10.1016/s0167-8140(98)00015-2.
A newly developed non-invasive immobilization frame for stereotactic radiotherapy is presented, which is intended to be used for both imaging (computed tomography (CT) and angiography) and radiotherapeutic procedures.
The frame is made of duraluminium so as to be stable and light and it has an elliptical shape. The immobilization is achieved using three stable locations on the patient's head, i.e. the upper dentition, the nose and the back of the neck. The fixation on the three locations ensures complete immobilization in all directions.
The immobilization frame can be fitted as many times as is needed to most heads. In order to assess the accuracy of relocation, repeated fittings on two volunteers and on 22 patients undergoing stereotactic treatment were performed (more than 200 mountings in total), which showed maximum anterior-posterior, inferior-superior and lateral reproducibility in positioning of less than 1 mm in all cases.
The in-house-constructed stereotactic frame is simple to use, easily made, non-invasive, relocatable and well tolerated by the patients, providing the possibility of multiple fractions. The major advantage of using such a non-invasive stereotactic frame is the flexibility in timing the different diagnostic procedures (CT and angiography) as well as providing the possibility to extend the use to large brain lesions (treatment without an additional collimator) where a high precision is also required. It also offers significant labour and cost saving over the invasive frames and the majority of the non-invasive frames. To date, 22 patients with ages varying between 12 and 70 years have been treated using this method.
介绍一种新开发的用于立体定向放射治疗的非侵入性固定框架，其旨在用于成像（计算机断层扫描（CT）和血管造影）及放射治疗程序。
该框架由硬铝制成，以确保稳定且轻便，呈椭圆形。通过患者头部的三个稳定位置，即上牙列、鼻子和颈部后方来实现固定。在这三个位置的固定确保了全方位的完全固定。
该固定框架可根据需要多次适配大多数头部。为评估重新定位的准确性，对两名志愿者和22名接受立体定向治疗的患者进行了重复适配（总共超过200次安装），结果显示在所有情况下，前后、上下和侧向定位的最大再现性均小于1毫米。
自制的立体定向框架使用简单、易于制作、非侵入性、可重新定位且患者耐受性良好，提供了多次分割治疗的可能性。使用这种非侵入性立体定向框架的主要优点在于，在安排不同诊断程序（CT和血管造影）的时间方面具有灵活性，同时还能够将其应用扩展至需要高精度的大脑大病变（无需额外准直器的治疗）。与侵入性框架和大多数非侵入性框架相比，它还显著节省了人力和成本。迄今为止，已有22名年龄在12岁至70岁之间的患者使用此方法接受了治疗。
