Tarjányi Z, Kalász H, Szebeni G, Hollósi I, Báthori M, Fürst S
Department of Pharmacology, Semmelweis University of Medicine, Budapest, Hungary.
J Pharm Biomed Anal. 1998 Aug;17(4-5):725-31. doi: 10.1016/s0731-7085(97)00227-6.
The metabolism and urinary elimination of both (-)-deprenyl and (+)-deprenyl have been studied. Gas-chromatographic analysis with mass specific detection indicated that the metabolism of (-)-deprenyl results in a large excess of methamphetamine compared to amphetamine, while the metabolism of (+)-deprenyl gave nearly equal amounts of amphetamine and methamphetamine. A novel deprenyl metabolite, phenylacetone, was also identified in our studies.
