Tanaka J, Yamashita M, Yamashita M, Kajigaya H
Department of Emergency and Critical Care Medicine, University of Tsukuba, Japan.
Vet Hum Toxicol. 1998 Aug;40(4):193-6.
Incidences of swallowing lithium batteries have been increasing. More severe tissue damage may be produced by the flow of electric current through tissue due to a lithium battery than a button alkali battery, because the former has the higher voltage of 3V. In this study, model CR2032 lithium batteries were fixed in the esophagus of 5 adult mongrel dogs for 15 or 30 min or 1, 2 or 5 h. On microscopical examination of the esophagus 15 min after fixation of the battery, necrosis was demonstrated from the lamina propria mucosa to the inner muscular layer. Thirty min after fixation of the battery, the esophageal epithelium had completely disappeared to form a blackish-brown area and the outer muscular layer was partially necrosed. Histological findings after 1, 2 or 5 h were similar to those after 30 min, and the blackish-brown area became larger with time. The necrosis extended to the trachea after 1 h. The necrosis developed sooner in tissue in contact with the lithium battery. An ingested lithium battery appears to be more dangerous than a button alkali battery unless it is removed quickly.
吞咽锂电池的发生率一直在上升。由于锂电池的电压为3V，高于纽扣碱性电池，因此锂电池电流通过组织时可能会造成更严重的组织损伤。在本研究中，将型号为CR2032的锂电池固定在5只成年杂种犬的食管中15或30分钟，或1、2或5小时。在电池固定15分钟后对食管进行显微镜检查，发现从黏膜固有层到内层肌肉均出现坏死。电池固定30分钟后，食管上皮完全消失，形成黑褐色区域，外层肌肉部分坏死。1、2或5小时后的组织学结果与30分钟后的相似，且黑褐色区域随时间增大。1小时后坏死扩展至气管。与锂电池接触的组织坏死发展更快。除非迅速取出，否则摄入的锂电池似乎比纽扣碱性电池更危险。
