Khalfa S, Micheyl C, Veuillet E, Collet L
CNRS UPRESA 5020, Neurosciences et Systèmes Sensoriels, Hôpital Edouard Herriot, Lyon, France.
Hear Res. 1998 Jul;121(1-2):29-34. doi: 10.1016/s0378-5955(98)00062-8.
Previous studies indicate a left-right asymmetry in the function of peripheral auditory system. Contralateral acoustic suppression of TEOAEs (transient evoked otoacoustic emissions) enables assessment of medial olivocochlear efferent system functioning, and has demonstrated that this system is more effective in the right than in the left ear. Moreover, TEOAE amplitudes are lower in the left than in the right ear. The aim of the present experiment was to verify firstly the absence of a relationship between medial efferent system asymmetry and TEOAE amplitude asymmetry, and secondly to study TEOAE input/output function slopes. There was no link between the asymmetries in TEOAE amplitude and in the medial efferent system functioning. Further, as previously shown, the medial olivocochlear system increased the TEOAE input/output function slopes. These TEOAE input/output function slopes seem to be consistent factors in peripheral asymmetry since the slope is lower in the right than in the left ear. Moreover, the lower the TEOAE amplitudes, the greater the TEOAE slopes. The slope asymmetry of the two ears could correspond to earlier saturation or a lower augmentation ability of the TEOAE response in the right ear, where the TEOAE amplitude is higher. This asymmetry in growth slopes reinforces the notion of peripheral auditory lateralization.
先前的研究表明，外周听觉系统的功能存在左右不对称性。对瞬态诱发耳声发射（TEOAEs）的对侧听觉抑制能够评估内侧橄榄耳蜗传出系统的功能，并且已经证明该系统在右耳比在左耳更有效。此外，左耳的TEOAE振幅低于右耳。本实验的目的，一是验证内侧传出系统不对称性与TEOAE振幅不对称性之间不存在关联，二是研究TEOAE输入/输出功能斜率。TEOAE振幅的不对称性与内侧传出系统功能的不对称性之间没有联系。此外，如先前所示，内侧橄榄耳蜗系统增加了TEOAE输入/输出功能斜率。这些TEOAE输入/输出功能斜率似乎是外周不对称性中的一致因素，因为右耳的斜率低于左耳。而且，TEOAE振幅越低，TEOAE斜率越大。两只耳朵的斜率不对称可能对应于右耳TEOAE反应的更早饱和或更低增强能力，右耳的TEOAE振幅更高。这种增长斜率的不对称性强化了外周听觉侧化的概念。
