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兔带血管软骨瓣气管重建术

Tracheal reconstruction with a vascularized cartilage flap in rabbits.

作者信息

Ergin N T, Koç C, Demirhan B, Dal T

机构信息

Department of Otolaryngology, Baskent University College of Medicine, Bahçelievler, Ankara, Turkey.

出版信息

Ann Otol Rhinol Laryngol. 1998 Jul;107(7):571-4. doi: 10.1177/000348949810700705.

Abstract

The relative merits of a vascularized autogenous cartilage flap (VACF) are discussed in reconstruction of tracheal defects in rabbits. Sixteen albino Vienna rabbits were divided into two groups of eight animals each. In all rabbits, a rectangular tracheal defect was created. In the experimental group, a VACF was designed on the left auricle. This island flap was then transposed through a subcutaneous tunnel to the trachea and used to repair the defect. In the control group, tracheal defects were reconstructed with free cartilage grafts. In histologic evaluations, it was found that the reconstructed site showed a greater degree of vascularization when a VACF was used, and the gap between the trachea and flap was filled with new cartilage tissue, to a much greater extent than with the free cartilage grafts. It is concluded that use of the VACF is a relatively safe and effective procedure for repairing tracheal defects.

摘要

本文讨论了带血管蒂自体软骨瓣(VACF)在兔气管缺损重建中的相对优点。16只白化维也纳兔被分为两组,每组8只。对所有兔子均制作一个矩形气管缺损。在实验组中,在左耳廓设计一个带血管蒂自体软骨瓣。然后将该岛状皮瓣通过皮下隧道转移至气管,用于修复缺损。在对照组中,采用游离软骨移植修复气管缺损。组织学评估发现,使用带血管蒂自体软骨瓣时,重建部位的血管化程度更高,气管与皮瓣之间的间隙填充有新的软骨组织,其程度远大于游离软骨移植。得出结论,使用带血管蒂自体软骨瓣是修复气管缺损的一种相对安全有效的方法。

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