Pedersen R C, Person D A
Department of Pediatrics, Tripler Army Medical Center, Honolulu, Hawaii.
Pediatr Neurol. 1998 Jul;19(1):69-73. doi: 10.1016/s0887-8994(98)00022-8.
A 16-year-old girl with longstanding polyarticular juvenile rheumatoid arthritis was referred from Chuuk State, Federated States of Micronesia, for evaluation and management of weakness and joint pains. She had a right hemiparesis with central facial weakness, polyarticular arthritis, and a dense cataract of the left eye with phthisis bulbi. Extensive evaluation using magnetic resonance angiography revealed vasculitis of the anterior and middle cerebral arteries. She was treated with "pulse" doses of methylprednisolone intravenously and she improved remarkably. Repeat angiography demonstrated dramatic improvement of the vasculitis. There is a paucity of literature regarding cerebral vasculitis in juvenile rheumatoid arthritis. That literature is reviewed, and our patient is discussed with regard to the few published reports.
一名来自密克罗尼西亚联邦楚克州的16岁长期患有多关节型幼年类风湿关节炎的女孩，因肌无力和关节疼痛前来接受评估和治疗。她有右侧偏瘫伴中枢性面瘫、多关节关节炎，左眼有致密性白内障伴眼球痨。使用磁共振血管造影进行的广泛评估显示大脑前动脉和中动脉血管炎。她接受了静脉注射“冲击”剂量的甲基强的松龙治疗，病情显著改善。重复血管造影显示血管炎有显著改善。关于幼年类风湿关节炎中的脑血管炎的文献很少。本文对该文献进行了综述，并结合少数已发表的报告对我们的患者进行了讨论。
