胸部计算机断层扫描和纵隔镜检查在结节病相关性葡萄膜炎诊断中的应用
Chest computed tomography and mediastinoscopy in the diagnosis of sarcoidosis-associated uveitis.
作者信息
Kosmorsky G S, Meisler D M, Rice T W, Meziane M A, Lowder C Y
机构信息
Division of Ophthalmology, Cleveland Clinic Foundation, OH 44195, USA.
出版信息
Am J Ophthalmol. 1998 Jul;126(1):132-4. doi: 10.1016/s0002-9394(98)00081-6.
PURPOSE
To report the usefulness of chest computed tomography and mediastinoscopy in diagnosing sarcoidosis in elderly patients with uveitis.
METHODS
Case reports. Two Caucasian women, aged 73 and 70 years, underwent evaluations for uveitis, which included chest computed tomography and mediastinoscopy.
RESULTS
A chest computed tomographic scan of each woman disclosed mediastinal lymphadenopathy and warranted mediastinal lymph node biopsy by mediastinoscopy. In both patients, histopathologic and microbiologic studies demonstrated sterile noncaseating granulomas consistent with the diagnosis of sarcoidosis.
CONCLUSIONS
The diagnosis of sarcoid-associated uveitis in the elderly may be facilitated by chest computed tomography, which may be more sensitive than conventional chest roentgenography. Laboratory studies of biopsied mediastinal nodes obtained by mediastinoscopy can confirm the diagnosis.
目的
报告胸部计算机断层扫描和纵隔镜检查在诊断老年葡萄膜炎患者结节病中的作用。
方法
病例报告。两名白种女性，年龄分别为73岁和70岁，接受了葡萄膜炎评估，包括胸部计算机断层扫描和纵隔镜检查。
结果
每名女性的胸部计算机断层扫描均显示纵隔淋巴结肿大，需要通过纵隔镜检查进行纵隔淋巴结活检。在两名患者中，组织病理学和微生物学研究均显示无菌性非干酪样肉芽肿，符合结节病的诊断。
结论
胸部计算机断层扫描可能比传统胸部X线检查更敏感，有助于诊断老年结节病相关性葡萄膜炎。通过纵隔镜检查获取的纵隔淋巴结活检的实验室研究可以确诊。
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