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特发性关节软骨钙质沉着症的脊柱改变

Spinal changes in idiopathic chondrocalcinosis articularis.

作者信息

Richards A J, Hamilton E B

出版信息

Rheumatol Rehabil. 1976 Aug;15(3):138-42. doi: 10.1093/rheumatology/15.3.138.

Abstract

The lumbar-spine radiographs of 67 patients with idiopathic chondrocalcinosis articularis were reviewed for disc calcification and other changes. Calcification was present in 21 (31%) of the patients, seen most frequently at the L 2-3 disc space. The 21 patients as a group were significantly older than the 46 patients without disc calcification, and also had a much higher incidence of chondrocalcinosis in peripheral joints. There was no association with back pain or spinal stiffness. The 21 patients with disc calcification included six patients with a destructive peripheral arthropathy, and three of them had destructive changes affecting the lumbar spine. Three patients with a destructive peripheral arthropathy were also included in the group without disc calcification, and one of these had a destructive arthritis of the lumbar spine. For comparison, there was a 55% incidence of spinal chondrocalcinosis in nine patients with primary hyperparathyroidism and peripheral joint chondrocalcinosis, and a 6% incidence in 100 anteroposterior lumbar spine radiograph 'controls', taken before intravenous urography, although in this latter group the changes were minimal and confined to the margin of a single disc in each case.

摘要

回顾了67例特发性关节软骨钙质沉着症患者的腰椎X光片,以观察椎间盘钙化及其他变化。21例(31%)患者存在钙化,最常见于L2-3椎间盘间隙。这21例患者作为一个群体,比46例无椎间盘钙化的患者年龄显著更大,且外周关节软骨钙质沉着症的发病率也高得多。与背痛或脊柱僵硬无关。21例有椎间盘钙化的患者中有6例患有破坏性外周关节病,其中3例有影响腰椎的破坏性改变。无椎间盘钙化组中也包括3例患有破坏性外周关节病的患者,其中1例有腰椎破坏性关节炎。作为对照,9例原发性甲状旁腺功能亢进症合并外周关节软骨钙质沉着症患者中,脊柱软骨钙质沉着症的发病率为55%;在静脉肾盂造影前拍摄的100例腰椎前后位X光片“对照者”中,发病率为6%,不过在后一组中,变化很小,且每例均局限于单个椎间盘边缘。

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