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Amifostine: a radioprotector in locally advanced head and neck tumors.

作者信息

Wagner W, Prott F J, Schonekas K G

机构信息

Paracelsus-Strahlenklinik, D-49076 Osnabruck, Germany.

出版信息

Oncol Rep. 1998 Sep-Oct;5(5):1255-7. doi: 10.3892/or.5.5.1255.

DOI:10.3892/or.5.5.1255
PMID:9683846
Abstract

Patients with locally advanced head and neck tumors were treated +/-amifostine (200 mg/m2, i.v.) before radiotherapy (5x 2 Gy, for 6 weeks). A significant decrease in side effects (p=0.034) using the oral assessment score and duration of mucositis (p=0.02) in the amifostine group was observed. Amifostine is feasible and effective, decreasing acute and late side effects in patients with head and neck tumors.

摘要

相似文献

1
Amifostine: a radioprotector in locally advanced head and neck tumors.
Oncol Rep. 1998 Sep-Oct;5(5):1255-7. doi: 10.3892/or.5.5.1255.
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Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head-and-neck cancer.氨磷汀预防性应用于预防头颈部癌放化疗引起的黏膜炎和口干症。
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Strahlenther Onkol. 1999 Nov;175 Suppl 4:30-3.

引用本文的文献

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Radiation-Induced Oral Mucositis.放射性口腔黏膜炎
Front Oncol. 2017 May 22;7:89. doi: 10.3389/fonc.2017.00089. eCollection 2017.
2
Post-radiation dental index: development and reliability.放疗后牙齿指数：制定与可靠性
Support Care Cancer. 2008 May;16(5):525-30. doi: 10.1007/s00520-007-0393-x. Epub 2008 Jan 15.
3
Prevention of radiation-induced mucositis.放射性口腔黏膜炎的预防。
Curr Oncol Rep. 2001 Jan;3(1):56-8. doi: 10.1007/s11912-001-0043-2.