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醛固酮增多症：1型糖尿病中一种罕见的非肾病性高血压病因。

Aldosterone excess: a rare non-nephrophathic cause of hypertension in type I diabetes.

作者信息

Chan N N, Feher M D

机构信息

Department of Clinical Pharmacology & Therapeutics, Chelsea & Westminster Hospital, London, UK.

出版信息

Postgrad Med J. 1998 Apr;74(870):235-6. doi: 10.1136/pgmj.74.870.235.

DOI:10.1136/pgmj.74.870.235
PMID:9683979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2360866/
Abstract

The aetiology of hypertension in type 1 diabetes is commonly due to the presence of diabetic nephrology. A rare case of hypertension in a patient with type 1 diabetes and no proteinuria is reported, where the investigation of borderline hypokalaemia allowed us to make a diagnosis of hyperaldosteronism due to bilateral adrenocortical hyperplasia. Secondary causes of hypertension should always be considered in all diabetic patients, particularly in the absence of clinical proteinuria.

摘要

1型糖尿病患者高血压的病因通常是糖尿病肾病。本文报告了1例1型糖尿病且无蛋白尿患者出现高血压的罕见病例，对临界性低钾血症的检查使我们诊断其为双侧肾上腺皮质增生所致的醛固酮增多症。所有糖尿病患者都应始终考虑高血压的继发性病因，尤其是在无临床蛋白尿的情况下。

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本文引用的文献

1
Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients.高血压患者中肾上腺及肾上腺外Conn综合征的患病率。
Arch Intern Med. 1996 Jun 10;156(11):1190-5.
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Diabetic nephropathy and arterial hypertension.糖尿病肾病与动脉高血压
Diabetologia. 1983 Jan;24(1):10-2. doi: 10.1007/BF00275939.
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The changing clinical spectrum of primary aldosteronism.原发性醛固酮增多症不断变化的临床谱。
Am J Med. 1983 Apr;74(4):641-51. doi: 10.1016/0002-9343(83)91022-7.
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The syndrome of primary aldosteronism.原发性醛固酮增多症综合征
Am J Med. 1970 Mar;48(3):343-56. doi: 10.1016/0002-9343(70)90065-3.
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Primary aldosteronism due to a malignant ovarian tumour.原发性醛固酮增多症由恶性卵巢肿瘤引起。
Aust N Z J Med. 1986 Feb;16(1):69-71. doi: 10.1111/j.1445-5994.1986.tb01123.x.
6
Autonomous aldosterone-secreting ovarian tumor.自主性分泌醛固酮的卵巢肿瘤。
Gynecol Oncol. 1990 May;37(2):284-9. doi: 10.1016/0090-8258(90)90349-p.
7
Primary aldosteronism due to a malignant ovarian tumor.源于恶性卵巢肿瘤的原发性醛固酮增多症。
J Clin Endocrinol Metab. 1975 Nov;41(5):809-19. doi: 10.1210/jcem-41-5-809.

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