Dermatologic manifestations of systemic disease.

As the body's point of contact with the weight-bearing surface, the foot resists abrasive forces and is constantly bombarded with dermatologic insults. It is the site of a variety of local and systemic afflictions, some which even indicate a state of relative emergency. Paying careful attention to the consideration and exclusion of serious or systemic conditions, this article presents an algorithmic approach that is useful in a clinical setting.