Bhatia A, Singh N, Arora V K, Gupta K
Department of Pathology, University College of Medical Sciences, Delhi, India.
Acta Cytol. 1998 Jul-Aug;42(4):865-8. doi: 10.1159/000331960.
To analyze the effects of a prospective peer review program on diagnostic accuracy in a routine cytopathology laboratory.
For the study, 4,836 consecutive cases subjected to fine needle aspiration cytology (FNAC) over a one-year period were used. Nine pathologists performed both reporting and peer review functions. Disagreements were classified into "diagnostic errors" and "diagnostic discrepancies," depending on their impact on patient care. The effect of this review on turnaround time was statistically analyzed. A retrospective review of 4,025 cases from the preceding year was performed for comparison.
Sixty-six cases with diagnostic disagreements were detected by prospective review. There were 28 diagnostic errors and 38 diagnostic discrepancies. The initial turnaround time for diagnostic FNAC in 90% of total cases was < 24 hours; mean delay for the remainder was 3.3 days. Prospective peer review added a further delay of 1 and 1.5 days, respectively. The number of diagnostic disagreements was significantly higher in the retrospective review (P < .01).
Prospective peer review of diagnostic FNAC resulted in improved accuracy of diagnosis and reduced potential for inappropriate therapy; however, turnaround time was significantly increased.
分析一项前瞻性同行评审计划对常规细胞病理学实验室诊断准确性的影响。
本研究采用了在一年时间内连续进行细针穿刺细胞学检查(FNAC)的4836例病例。九位病理学家同时履行报告和同行评审职责。根据对患者治疗的影响,将分歧分为“诊断错误”和“诊断差异”。对此次评审对周转时间的影响进行了统计学分析。对前一年的4025例病例进行回顾性审查以作比较。
前瞻性评审发现66例存在诊断分歧的病例。其中有28例诊断错误和38例诊断差异。90%的病例中FNAC诊断的初始周转时间<24小时;其余病例的平均延迟时间为3.3天。前瞻性同行评审分别又增加了1天和1.5天的延迟。回顾性审查中诊断分歧的数量显著更高(P<.01)。
对FNAC诊断进行前瞻性同行评审可提高诊断准确性并降低不适当治疗的可能性;然而,周转时间显著延长。