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铸造工人中尘肺病和慢性支气管炎的患病率。

Prevalence of pneumoconiosis and chronic bronchitis in foundry workers.

作者信息

Kärävä R, Hernberg S, Koskela R S, Luoma K

出版信息

Scand J Work Environ Health. 1976;2 Suppl 1:64-72. doi: 10.5271/sjweh.2830.

Abstract

The prevalence of pneumoconiosis, chronic bronchitis, and impaired lung function was studied among those 1,000 foundry workers (response rate 93.1%) with the longest exposure time (minimum 4.2, mean 17, SD 9 years) from a representative sample of 20 foundries. Pneumoconiosis was diagnosed from 100 x 100 mm radiographs, and the false positives and false negatives were evaluated from normal-size radiographs from all those with a positive finding and a sample of those with a negative finding. Chronic bronchitis was studied by means of a translation of the MRC Short Questionnarie on Respiratory Symptoms. Forced vital capacity and forced expiratory volume in 1 s were measured with a Vitalograph Single Breath Wedge Spirometer, and the FEV % was calculated from these variables. The subjects were grouped according to smoking habits and dust exposure, which could be fairly well evaluated from measurements performed in connection with the health survey. All comparisons were made between different subcategories. The overall prevalence of pneumoconiosis was 3.8%, when allowance had been made for false positive and false negative findings. Most cases were mild. Chronic bronchitis occurred more frequently among those occupied in jobs classified as dusty. Smoking also strongly increased its prevalence; a combination of both exposures produced the strongest effect. The effect of smoking was also evident as an impairment of lung function; however, no such effect of dust exposure could be shown in this material. Since this was a prevalence study, the selective removal of workers from dusty jobs probably led to underestimates of all the health effects studied. In spite of the effect of selection excess bronchitis could be demonstrated in workers from dusty environments. Therefore effective dust control must be initiated not only with regard to silica dust but also with respect to total dust.

摘要

对来自20家铸造厂的具有代表性样本中暴露时间最长(最短4.2年,平均17年,标准差9年)的1000名铸造工人(应答率93.1%)进行了尘肺病、慢性支气管炎和肺功能受损患病率的研究。尘肺病通过100×100mm的X光片诊断,并从所有阳性结果者的正常尺寸X光片以及部分阴性结果者的样本中评估假阳性和假阴性情况。慢性支气管炎通过对医学研究委员会呼吸症状简短问卷进行翻译来研究。使用肺活量计单次呼吸楔形肺量计测量用力肺活量和1秒用力呼气量,并根据这些变量计算FEV%。根据吸烟习惯和粉尘暴露情况对受试者进行分组,这可以通过与健康调查相关的测量相当准确地评估。所有比较均在不同子类别之间进行。在考虑了假阳性和假阴性结果后,尘肺病的总体患病率为3.8%。大多数病例为轻度。慢性支气管炎在从事分类为有粉尘工作的人群中更为常见。吸烟也显著增加了其患病率;两种暴露因素结合产生的影响最强。吸烟对肺功能的损害也很明显;然而,在该研究材料中未显示出粉尘暴露有此类影响。由于这是一项患病率研究,从有粉尘工作岗位上选择性地调离工人可能导致对所研究的所有健康影响的低估。尽管存在选择效应,但在有粉尘环境的工人中仍可证明存在过多的支气管炎病例。因此,不仅必须针对二氧化硅粉尘,而且必须针对总粉尘启动有效的粉尘控制措施。

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