Coste A, Idrissi F, Beautru R, Lenoir G, Reinert P, Manach Y, Peynegre R
Service d'O.R.L. et de Chirurgie Cervico-Faciale, Centre Hospitalo-Universitaire Henri Mondor de Créteil, Université Paris XII.
Ann Otolaryngol Chir Cervicofac. 1997;114(4):99-104.
Sinusitis, with sometimes severe symptoms, are frequent in cystic fibrosis (CF). The aim of this mild-term retrospective study was to evaluate the functional and anatomical results of functional endoscopic ethmoidectomy (FEE) in 12 patients with CF. Nasal polyposis (9 cases) and medialization of the nasomaxillary wall (3 cases) were detected during endoscopic examination. Bilateral and multifocal opacities of the paranasal sinuses were present on the CT-scan images in all cases. A FEE was performed in 11 cases and in 1 case, only the anterior ethmoid was opened. Symptoms improved or disappeared in 9/12 cases between 1 and 3 years of follow-up and in 5/7 cases after 3 years of follow-up. A good or mild anatomical result was recorded in 6/12 cases between 1 and 3 years of follow-up and in 5/7 cases after 3 years of follow-up. During follow-up, a new surgical procedure (limited in 8 patients and complete in 3 patients) was often necessary.
It is reasonable to propose FEE in CF patients with chronic sinusitis presenting severe symptoms with the aim of a substantial functional but not anatomical improvement.
鼻窦炎在囊性纤维化（CF）患者中很常见，有时症状严重。这项中期回顾性研究的目的是评估12例CF患者功能性鼻内镜筛窦切除术（FEE）的功能和解剖学结果。在内镜检查中发现鼻息肉（9例）和鼻上颌壁内移（3例）。所有病例的CT扫描图像均显示双侧和多灶性鼻窦混浊。11例行FEE，1例仅开放前筛窦。随访1至3年，9/12例症状改善或消失；随访3年后，5/7例症状改善或消失。随访1至3年，6/12例获得良好或轻度解剖学结果；随访3年后，5/7例获得良好或轻度解剖学结果。随访期间，经常需要进行新的手术（8例为局限性手术，3例为完全手术）。
对于患有慢性鼻窦炎且症状严重的CF患者，为了实现显著的功能改善而非解剖学改善，提议进行FEE是合理的。
