Forlenza O V, Vieira Filho A H, Machado L dos R, Nóbrega J P, de Barros N G
Laboratório de Investigações Médicas (LIM-23) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brasil.
Arq Neuropsiquiatr. 1998 Mar;56(1):45-52. doi: 10.1590/s0004-282x1998000100007.
To determine the frequency and features of psychiatric morbidity in a cross-section of 38 outpatients with neurocysticercosis.
Diagnosis of neurocysticercosis was established by CT scan, MRI and CSF analysis. Psychiatric diagnoses were made by using the Present State Examination and the Schedule for Affective Disorders and Schizophrenia. Lifetime version; cognitive state was assessed by Mini-Mental State Examination and Strub & Black's Mental Status Examination.
Depression was the most frequent psychiatric diagnosis (52.6%) as shown by PSE. Active disease and intracranial hypertension were associated with higher psychiatric morbidity, and previous history of mood disorders was strongly related to current depression.
Depression syndromes are frequent in patients with neurocysticercosis. The extent to which organic mechanisms related to brain lesions may underlie the observed mental changes is yet unclear, though the similar sex distribution of patients with and without depression, as well as the above mentioned correlations, provide further evidence of the role played by organic factors in the cause of these syndromes. The results of this study are discussed in the light of the data available for other organic psychiatric disorders.
确定38例神经囊尾蚴病门诊患者横断面中精神疾病的发病率及特征。
通过CT扫描、MRI和脑脊液分析确诊神经囊尾蚴病。采用现况检查及情感障碍和精神分裂症检查表进行精神疾病诊断；采用简易精神状态检查表和斯特鲁布与布莱克精神状态检查表评估认知状态。
现况检查显示，抑郁症是最常见的精神疾病诊断（52.6%）。活动性疾病和颅内高压与较高的精神疾病发病率相关，既往情绪障碍史与当前抑郁症密切相关。
神经囊尾蚴病患者中抑郁症综合征很常见。尽管有抑郁症和无抑郁症患者的性别分布相似，以及上述相关性，但与脑病变相关的器质性机制在多大程度上可能是观察到的精神变化的基础尚不清楚，这进一步证明了器质性因素在这些综合征病因中所起的作用。根据其他器质性精神障碍的现有数据对本研究结果进行了讨论。
