Ouhabi H, Bourazza A, Rouimi A, Boutaleb N, Mosseddaq R
Service de Neurologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Rev Neurol (Paris). 1997 Dec;153(12):790-1.
We report a clinical association of diffuse scleroderma and amyotrophic lateral sclerosis (ALS) in two patients. Scleroderma was diagnosed on skin, digestive, osteoarticular, pulmonary lesions and inflammatory syndrome. ALS was suspected on the association of diffuse amyotrophy, fasciculations, pyramidal tract involvement and electrophysiological data. Chronic medulla ischemia and or immune abnormalities are proposed as potential pathological mechanisms for ALS but fortuitous association can not be excluded.
