Localization of receptors for endocytosis of lysosomal enzymes on different brain cells.

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作者信息

Schluff P, Flott-Rahmel B, Gieselmann V, Zimmer P, Das A, Ullrich K

机构信息

Department of Pediatrics, University of Hamburg, Germany.

出版信息

J Inherit Metab Dis. 1998 Jun;21(3):313-7. doi: 10.1023/a:1005305213832.

DOI:10.1023/a:1005305213832

PMID:9686384

Abstract

摘要

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Localization of receptors for endocytosis of lysosomal enzymes on different brain cells.

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Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis.大鼠大脑含有高水平的甘露糖-6-磷酸化糖蛋白，包括溶酶体酶和棕榈酰蛋白硫酯酶，后者是一种与婴儿神经元脂褐质沉积症有关的酶。

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