Suppr超能文献

罗斯手术的中期结果。

Mid-term results of the Ross procedure.

作者信息

Daenen W, Jalali H, Eyskens B, Gewillig M

机构信息

Department of Cardiac Surgery, Gasthuisberg University Hospital, Leuven, Belgium.

出版信息

Eur J Cardiothorac Surg. 1998 Jun;13(6):673-7. doi: 10.1016/s1010-7940(98)00090-6.

Abstract

METHODS

Fifty patients underwent a Ross operation between June 1991 and October 1996. Preoperative diagnosis was: congenital aortic valve disease (31 patients), complex left ventricular outflow tract (LVOT) obstruction (11 patients), outgrowth of a small aortic valve prosthesis (five patients) and valve endocarditis (three patients). Half of the interventions were reoperations. All operations were root replacements. A pulmonary homograft was used in 45 patients. An aorticoventriculoplasty was combined with the root replacement in the 16 patients with LVOT obstruction and a too small aortic valve prosthesis. An enlargement or reduction plasty of the ascending aorta was necessary in seven patients.

RESULTS

The mean age was 20.9 years (range: 2.5-54 years). The mean follow up was 34.2 +/- 21 months and was 94% complete. Two patients died after 8 days (low cardiac output due to myocardial fibrosis) and 17.4 months (sudden death), respectively, resulting in a survival of 95 +/- 4% at 4 years. Those two deaths occurred in the group of patients undergoing Ross procedure and aorticoventriculoplasty. Two autografts were replaced after respectively 2 days (technical failure) and 44 months (progressive root dilatation) resulting in a reoperation-free incidence of 93 +/- 6% at 4 years. Other postoperative major complications occurred in six patients. All survivors had regular echo-Doppler examination. All autografts except one had a systolic gradient below 10 mmHg at the last examination. Thirty-four autografts had no leak, ten showed grade 1-2 regurgitation. Two patients showed a higher than grade 3 regurgitation: one leak remains stable with normal left ventricular dimensions and function, one autograft was replaced by a mechanical valve.

CONCLUSION

This experience demonstrates that the medium-term results of the Ross procedure are excellent even in complex LVOT obstructions.

摘要

方法

1991年6月至1996年10月期间,50例患者接受了罗斯手术。术前诊断为:先天性主动脉瓣疾病(31例)、复杂左心室流出道(LVOT)梗阻(11例)、小型主动脉瓣人工瓣膜增生(5例)和瓣膜心内膜炎(3例)。半数干预措施为再次手术。所有手术均为根部置换。45例患者使用了肺动脉同种异体移植物。16例LVOT梗阻且主动脉瓣人工瓣膜过小的患者,在根部置换的同时进行了主动脉心室成形术。7例患者需要进行升主动脉扩大或缩小成形术。

结果

平均年龄为20.9岁(范围:2.5 - 54岁)。平均随访时间为34.2±21个月,随访完成率为94%。两名患者分别在术后8天(因心肌纤维化导致低心输出量)和17.4个月(猝死)死亡,4年生存率为95±4%。这两例死亡发生在接受罗斯手术和主动脉心室成形术的患者组中。两枚自体移植物分别在术后2天(技术失败)和44个月(进行性根部扩张)后被置换,4年无再次手术发生率为93±6%。其他术后主要并发症发生在6例患者中。所有幸存者均接受了定期超声多普勒检查。除1例之外,所有自体移植物在最后一次检查时收缩期压差均低于10 mmHg。34枚自体移植物无反流,10枚显示1 - 2级反流。两名患者显示反流高于3级:1例反流保持稳定,左心室大小和功能正常,1枚自体移植物被机械瓣膜置换。

结论

该经验表明,即使在复杂的LVOT梗阻病例中,罗斯手术的中期结果也非常出色。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验