Antiangiogenic gene therapy.
作者信息
Folkman J
机构信息
Department of Surgery, Children's Hospital, Boston, MA 02115, USA.
出版信息
Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9064-6. doi: 10.1073/pnas.95.16.9064.
Abstract
摘要
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Antiangiogenic gene therapy.抗血管生成基因疗法
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本文引用的文献
1
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2.靶向内皮细胞特异性受体酪氨酸激酶Tie2的抗血管生成基因治疗
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8829-34. doi: 10.1073/pnas.95.15.8829.
2
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate.天然可溶性血管内皮生长因子受体的旁分泌表达可抑制肿瘤生长、转移及死亡率。
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8795-800. doi: 10.1073/pnas.95.15.8795.
3
Gene therapy for therapeutic myocardial angiogenesis: a promising synthesis of two emerging technologies.用于治疗性心肌血管生成的基因疗法：两种新兴技术的有望结合。
Nat Med. 1998 Jun;4(6):739-42. doi: 10.1038/nm0698-739.
4
Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest.血管抑素基因转移：通过阻断与有丝分裂停滞相关的内皮细胞增殖来抑制体内肿瘤生长。
Proc Natl Acad Sci U S A. 1998 May 26;95(11):6367-72. doi: 10.1073/pnas.95.11.6367.
5
A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.一种人类纤维肉瘤通过血小板反应蛋白-1抑制全身血管生成和实验性转移瘤的生长。
Proc Natl Acad Sci U S A. 1998 May 26;95(11):6343-8. doi: 10.1073/pnas.95.11.6343.
6
Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases.血管抑素cDNA在小鼠纤维肉瘤中的表达可抑制原发性肿瘤生长并使转移灶长期休眠。
J Clin Invest. 1998 Mar 1;101(5):1055-63. doi: 10.1172/JCI1558.
7
Gene therapy strategies for tumor antiangiogenesis.肿瘤抗血管生成的基因治疗策略。
J Natl Cancer Inst. 1998 Feb 18;90(4):273-86. doi: 10.1093/jnci/90.4.273.
8
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.实验性癌症的抗血管生成疗法不会诱导获得性耐药。
Nature. 1997 Nov 27;390(6658):404-7. doi: 10.1038/37126.
9
Why are we doing so much cancer gene therapy? Disentangling the scientific basis from the origins of gene therapy.我们为何要开展如此多的癌症基因治疗？从基因治疗的起源梳理其科学基础。
Gene Ther. 1997 Aug;4(8):755-6. doi: 10.1038/sj.gt.3300494.
10
Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.利用可溶性受体抑制肿瘤血管生成确定了Tie2在病理性血管生长中的作用。
J Clin Invest. 1997 Oct 15;100(8):2072-8. doi: 10.1172/JCI119740.
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