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硬膜外脓肿并发硬膜外麻醉和镇痛。文献分析。

Epidural abscess complicating epidural anesthesia and analgesia. An analysis of the literature.

作者信息

Kindler C H, Seeberger M D, Staender S E

机构信息

Department of Anesthesia, Kantonsspital, University of Basel, Switzerland.

出版信息

Acta Anaesthesiol Scand. 1998 Jul;42(6):614-20. doi: 10.1111/j.1399-6576.1998.tb05291.x.

Abstract

BACKGROUND

Epidural abscess is a serious complication of epidural block. Because of its low incidence, the risk factors and the symptoms and cause of epidural abscess related to epidural anesthesia and analgesia are not well known by anesthesiologists.

METHODS

A computer-assisted search of the literature on epidural catheter-related abscess was performed to describe the clinical course and bacteriology of this complication, to determine possible risk factors, and to assess the index of suspicion among physicians.

RESULTS

Forty-two patients with a catheter-related epidural abscess were identified. Only in 15 patients was the correct diagnosis considered initially. The time from insertion of the epidural catheter to symptoms varied between 1 and 60 d. Initial symptoms included back pain, fever, and leukocytosis. The time from symptoms to treatment was a few hours to 108 d. Interval from first symptoms to treatment was significantly longer in patients with persistent neurologic deficits compared with patients who completely recovered. Staphylococcus aureus was the most common etiologic agent. Outcome was reported in 39 patients, but only 19 made a full recovery.

CONCLUSION

The index of suspicion among anesthesiologists, other physicians and nurses taking care of patients with epidural catheters must be increased for this complication; this should shorten the interval from symptoms to treatment and lower the incidence of neurological sequelae.

摘要

背景

硬膜外脓肿是硬膜外阻滞的一种严重并发症。由于其发病率较低,麻醉医生对与硬膜外麻醉和镇痛相关的硬膜外脓肿的危险因素、症状及病因了解不足。

方法

通过计算机辅助检索与硬膜外导管相关脓肿的文献,以描述该并发症的临床过程和细菌学特征,确定可能的危险因素,并评估医生的怀疑指数。

结果

共确定42例与导管相关的硬膜外脓肿患者。最初仅15例患者被正确诊断。从硬膜外导管置入到出现症状的时间为1至60天。初始症状包括背痛、发热和白细胞增多。从出现症状到治疗的时间为几小时至108天。与完全康复的患者相比,持续存在神经功能缺损的患者从首次出现症状到治疗的间隔时间明显更长。金黄色葡萄球菌是最常见的病原体。39例患者报告了预后情况,但只有19例完全康复。

结论

对于硬膜外导管置管患者,麻醉医生及其他医护人员对该并发症的怀疑指数必须提高;这应能缩短从出现症状到治疗的间隔时间,并降低神经后遗症的发生率。

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