Lisander B, Ivarsson I, Jacobsson S A
Department of Anaesthesiology and Intensive Care, University Hospital, Linköping, Sweden.
Acta Anaesthesiol Scand. 1998 Jul;42(6):707-12. doi: 10.1111/j.1399-6576.1998.tb05305.x.
The efficacy of intraoperative salvage and washing of wound blood and the predictors of allogeneic red cell transfusions in prosthetic hip surgery are insufficiently known.
In 96 patients, undergoing primary or revision surgery, salvaged and washed red cells and, if necessary, allogeneic blood were used to keep haematocrit not lower than 33%. The bleeding of red cells during hospital stay was calculated from the red cell balance. The preoperative red cell reserve (mililitres of red cells in excess of a haematocrit of 33%) was estimated and the difference between this volume and the total bleeding of red cells was retrospectively used to classify patients with regard to the need for red cells. Stepwise regression analysis was used to define patient-related variables associated with allogeneic blood transfusion.
Preoperative knowledge of the type of operation (primary, revision), the preoperative red cell reserve, and the body mass could predict roughly half of the need for banked blood (r2 = 0.45). Only one-third of the total bleeding of red cells was retransfused. For complete avoidance of allogeneic blood, autotransfusion was most effective in patients with a moderate need (0-4 u). However, 32% of such patients required allogeneic blood.
Autotransfusion has a limited efficacy to decrease the need for allogeneic blood, and other blood-saving methods should be added for this purpose. It is difficult to predict the need for allogeneic blood preoperatively.
人工髋关节置换手术中术中回收与冲洗伤口血液的效果以及异体红细胞输血的预测因素尚不清楚。
对96例行初次手术或翻修手术的患者,使用回收并洗涤的红细胞,必要时输注异体血,以维持血细胞比容不低于33%。根据红细胞平衡计算住院期间红细胞的出血量。估算术前红细胞储备量(血细胞比容超过33%时的红细胞毫升数),并根据该储备量与红细胞总出血量的差值,对患者的红细胞需求情况进行回顾性分类。采用逐步回归分析确定与异体输血相关的患者相关变量。
手术类型(初次手术、翻修手术)、术前红细胞储备量和体重等术前信息可大致预测约一半的库存血需求(r2 = 0.45)。仅三分之一的红细胞总出血量得到回输。对于完全避免异体输血,自体输血在需求适中(0 - 4单位)的患者中最为有效。然而,此类患者中有32%仍需要异体输血。
自体输血在减少异体输血需求方面效果有限,为此应添加其他血液节约方法。术前难以预测异体输血的需求。