Gueye S M, Diop S N, Ba M, Dagadou E K, Fall P A, Sow M A, Mensah A
Service d'Urologie, Hôpital Aristide Le Dantec, Dakar, Sénégal.
Prog Urol. 1998 Jun;8(3):377-81.
The objective of this study was to report the epidemiological profile of erectile dysfunction in a population of diabetic men.
This was a prospective study including 431 diabetic patients seen in the outpatients department. 69 of these patients suffered from erectile dysfunction. A control group of 138 patients was randomly selected according to age from among the remaining 362 patients. Each patient was submitted to complete clinical examination. The medical and surgical history, particularly vascular, neurological, endocrine and urological, was recorded. The patient's smoking and drinking habits and treatment with any antidiabetic or other drugs were also recorded. Statistical analysis was performed according to the case-control method. The limit of significance was p < 0.05.
The overall prevalence of erectile dysfunction was 16%. This rate is lower than those reported in the literature. Among the various risk factors, only complications of diabetes, especially neurological complications, were clearly correlated with the risk of erectile dysfunction (p = 0.0004). Similarly, the prevalence of erectile dysfunction increased with the duration of diabetes (p = 0.049).
The prevalence of erectile dysfunction in diabetic patients often appears to be overestimated in the literature. Methodological biases would explain the marked variation of reported prevalence rates. In contrast, our study confirms previous reports that neurological factors play a predominant role.
本研究的目的是报告糖尿病男性人群中勃起功能障碍的流行病学概况。
这是一项前瞻性研究，纳入了431名门诊就诊的糖尿病患者。其中69名患者患有勃起功能障碍。从其余362名患者中根据年龄随机选取138名患者作为对照组。每位患者均接受了全面的临床检查。记录了患者的内科和外科病史，尤其是血管、神经、内分泌和泌尿系统病史。还记录了患者的吸烟和饮酒习惯以及使用任何抗糖尿病药物或其他药物的治疗情况。根据病例对照法进行统计分析。显著性水平为p < 0.05。
勃起功能障碍的总体患病率为16%。该比率低于文献报道的比率。在各种危险因素中，只有糖尿病并发症，尤其是神经并发症，与勃起功能障碍的风险明显相关（p = 0.0004）。同样，勃起功能障碍的患病率随糖尿病病程的延长而增加（p = 0.049）。
文献中糖尿病患者勃起功能障碍的患病率似乎常常被高估。方法学偏倚可以解释所报道患病率的显著差异。相比之下，我们的研究证实了先前的报道，即神经因素起主要作用。
