Sandler U, Wyler A
Jerusalem College of Technology, Israel. SandlereMath.JCT.AC.IL
J Theor Biol. 1998 Jul 7;193(1):85-90. doi: 10.1006/jtbi.1998.0683.
In this paper we show that the gene transcription velocity can depend exponentially on the first moments of the base pair distribution in DNA. As the major fraction of the DNA of eucaryotes consists of non-coding sequences of base pairs and these determine the statistical characteristics of the base pair's ordering, non-coding DNA plays an important role in the functioning of the genetic apparatus. In particular, it enables a new independent mechanism for the gradual regulation of gene expression in eucaryotes.
在本文中，我们表明基因转录速度可能指数依赖于DNA中碱基对分布的一阶矩。由于真核生物DNA的主要部分由碱基对的非编码序列组成，并且这些序列决定了碱基对排列的统计特征，因此非编码DNA在遗传装置的功能中起着重要作用。特别是，它为真核生物中基因表达的逐步调节提供了一种新的独立机制。
