亚综合征抑郁症中血小板对血清素的细胞内钙反应。
The platelet intracellular calcium response to serotonin in subsyndromal depression.
作者信息
Berk M, Mitchell V S, Plein H
机构信息
Department of Psychiatry, University of the Witwatersrand Medical School, Parktown, South Africa.
出版信息
Int Clin Psychopharmacol. 1998 May;13(3):107-10. doi: 10.1097/00004850-199805000-00002.
The relationship of subsyndromal depression to syndromal depression is unclear. Increased sensitivity of platelet serotonin type 2 receptor has been reported in depression using the Fura-2 technique. The sensitivity of the platelet serotonin type 2 receptor was assessed using the Fura-2 method in 16 patients with subsyndromal depression and 14 controls. The patient group had higher numerical values of both basal and serotonin-stimulated levels of platelet intracellular calcium that did not however reach statistical significance.
亚综合征抑郁与综合征抑郁之间的关系尚不清楚。使用Fura-2技术的研究报告称，抑郁症患者血小板5-羟色胺2型受体的敏感性增加。本研究采用Fura-2方法，对16例亚综合征抑郁患者和14名对照者的血小板5-羟色胺2型受体敏感性进行了评估。患者组血小板细胞内钙的基础水平和5-羟色胺刺激水平的数值均较高，但未达到统计学显著性。
Zotero 插件