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The genetics of alcoholism.

作者信息

Goate A M, Edenberg H J

机构信息

Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

出版信息

Curr Opin Genet Dev. 1998 Jun;8(3):282-6. doi: 10.1016/s0959-437x(98)80082-8.

DOI:10.1016/s0959-437x(98)80082-8
PMID:9691005
Abstract

Recently, the first genome-wide searches for genes predisposing to or protecting against the development of alcohol dependence in humans have been carried out. Genetic studies in animal models of alcohol-related behaviors have also identified candidate chromosomal regions and potential candidate genes that can be tested in human populations.

摘要

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Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2.
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BMC Genet. 2005 Mar 1;6:11. doi: 10.1186/1471-2156-6-11.