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儿童滤泡性甲状腺癌的溶骨性颅骨转移

Lytic skull metastasis from a follicular thyroid carcinoma in a child.

作者信息

Kim S H, Kosnik E, Madden C, Morran S, Rusin J, Gordon T, Boue D

机构信息

Division of Neurosurgery, Children's Hospital, The Ohio State University Hospitals, Columbus 43210, USA.

出版信息

Pediatr Neurosurg. 1998 Feb;28(2):84-8. doi: 10.1159/000028626.

Abstract

We present a case of solitary lytic skull metastasis from a follicular thyroid carcinoma in a child. Salient clinical features, radiological findings, and histological distinctions of the metastatic skull tumor are described. Excision of the skull tumor followed by total thyroidectomy and (131)I-radioablation therapy has resulted in good short-term outcome. This is the first published report of a metastatic skull lesion from a follicular thyroid carcinoma in a child. Such a malignant lesion can radiologically mimic a benign skull tumor and should be considered in the differential diagnosis of a solitary lytic skull lesion with a sclerotic margin.

摘要

我们报告一例儿童滤泡性甲状腺癌单发溶骨性颅骨转移病例。描述了转移性颅骨肿瘤的显著临床特征、影像学表现及组织学差异。颅骨肿瘤切除后行甲状腺全切及碘-131放射消融治疗,取得了良好的短期疗效。这是首例发表的儿童滤泡性甲状腺癌颅骨转移病变报告。这种恶性病变在影像学上可酷似良性颅骨肿瘤,在鉴别诊断边缘硬化的单发溶骨性颅骨病变时应予以考虑。

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