Young D, Becerra M, Kopec D, Echols S
U.S. EPA, Western Ecology Division, Newport, OR 97365, USA.
Chemosphere. 1998 Aug;37(4):711-33. doi: 10.1016/s0045-6535(98)00075-7.
Here we report a validated technique for quantifying up to 20 specific PCB congeners in 1-2 g samples of whole blood with a detection limit below 1 ng/g (ppb) wet weight. Specimens were analyzed from 14 harbor seals sampled in south San Francisco Bay, California during 1991-1992. Ratios of specific congeners to PCB-153, and other aspects of congener pattern, agreed with published values for PCB's detected in seal blood. PCB-153 constituted 30 percent of our sigma PCB values. The mean sigma PCB concentration for the San Francisco Bay seals was 50 ppb, about three times the average level reported for blood of captive seals fed exclusively on fish from the Baltic's PCB-contaminated Dutch Wadden Sea. Such experimental populations have exhibited depressed reproductive success and impaired immune function. These findings support concerns about the ecological effects of PCB contamination in San Francisco Bay.
在此，我们报告了一种经过验证的技术，可对1至2克全血样本中的多达20种特定多氯联苯同系物进行定量分析，检测限低于1纳克/克（湿重）。分析了1991年至1992年期间在加利福尼亚州旧金山湾南部采集的14只斑海豹的样本。特定同系物与多氯联苯-153的比例以及同系物模式的其他方面，与海豹血液中检测到的多氯联苯的已发表值相符。多氯联苯-153占我们的总多氯联苯值的30%。旧金山湾海豹的总多氯联苯平均浓度为50纳克/克，约为仅以来自受多氯联苯污染的波罗的海荷兰瓦登海鱼类为食的圈养海豹血液平均水平的三倍。此类实验种群已出现繁殖成功率下降和免疫功能受损的情况。这些发现支持了对旧金山湾多氯联苯污染的生态影响的担忧。
