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[针吸睾丸活检在男性不育诊断中的应用]

[Needle testicular biopsy in the diagnosis of male infertility].

作者信息

Wolski J K, Kluge P, Kozioł K, Lewandowski P, Biarda B, Wysocki J

机构信息

Prywatnej Przychodni Leczenia Niepłodności Novum, Warszawa.

出版信息

Ginekol Pol. 1998 Jun;69(6):541-4.

PMID:9695380
Abstract

OBJECTIVES

Evaluation of testicular tissue is very important diagnostic procedures in cryptozoospermia and azoospermia. It is verified the patient for treatment (stimulation spermatogenesis), for micromanipulation ICSI or for insemination donor semen procedure. Surgical biopsy is very popular between andrologist and urologist, but needle biopsy seems to be easier and safer.

DESIGN

The authors present their experience with needle testicular biopsy during the diagnosis patients with azoospermia or cryptozoospermia and the men with paraplegia after trauma and without ejaculation.

MATERIAL AND METHODS

The study group included 63 biopsies in 58 men with azoospermia and severe oligoasthenozoospermia (cryptozoospermia) and 2 with paraplegia. The specimens were taken from 125 testes under general anesthesia (i.v-Diprivan, Propofol, Zeneca and Fentanyl) using biopsy needle from Hepafix B. Braun Melsungen, Germany. All procedures were performed as a day case.

RESULTS

In 95% specimens were adequate for histopathological investigations and for planning the treatment. Only one complication (0, 8%) -small haematoma testis was observed.

CONCLUSIONS

The needle biopsy of testicular tissue is sufficiency in histopathological examination, safe for patients and easy for urologists. The total cost is much more lower than cost of surgical biopsy.

摘要

目的

睾丸组织评估是隐睾症和无精子症非常重要的诊断程序。它用于确定患者是否适合治疗(刺激精子发生)、进行显微操作卵胞浆内单精子注射(ICSI)或供精人工授精程序。手术活检在男科医生和泌尿外科医生中非常普遍,但穿刺活检似乎更简便、更安全。

设计

作者介绍了他们在诊断无精子症或隐睾症患者以及创伤后截瘫且无射精功能的男性时进行睾丸穿刺活检的经验。

材料与方法

研究组包括对58例无精子症和严重少弱精子症(隐睾症)患者以及2例截瘫患者进行的63次活检。在全身麻醉(静脉注射得普利麻、丙泊酚、阿斯利康公司产品和芬太尼)下,使用德国贝朗医疗公司生产的Hepafix穿刺针从125个睾丸获取标本。所有操作均作为日间手术进行。

结果

95%的标本足以进行组织病理学检查并用于制定治疗方案。仅观察到1例并发症(0.8%)——睾丸小血肿。

结论

睾丸组织穿刺活检在组织病理学检查中足够,对患者安全,且对泌尿外科医生来说操作简便。总成本比手术活检低得多。

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1
[Needle testicular biopsy in the diagnosis of male infertility].[针吸睾丸活检在男性不育诊断中的应用]
Ginekol Pol. 1998 Jun;69(6):541-4.
2
[Percutaneous sperm retrieval for ICSI procedures in men with obstructive azoospermia: ICSI-PESA and ICSI-TESE micromanipulation: our experience].[梗阻性无精子症男性行卵胞浆内单精子注射(ICSI)手术时的经皮精子采集:ICSI-经皮附睾精子抽吸术和ICSI-睾丸精子提取显微操作:我们的经验]
Ginekol Pol. 1998 Jun;69(6):545-50.
3
A comparison between open and percutaneous needle biopsies in men with azoospermia.无精子症男性患者开放式与经皮穿刺针活检的比较。
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Hum Reprod. 1995 Oct;10(10):2595-9.
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J Obstet Gynaecol. 2002 Sep;22(5):527-31. doi: 10.1080/0144361021000003690.
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[Treatment of infertility in non-obstructive azoospermia using the TESE (testicular sperm extraction) method--clinical study].
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Testicular needle biopsy in diagnosis of infertility.睾丸穿刺活检在不孕症诊断中的应用
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[Infertility due to azoospermia. Causes, examination methods and therapeutic strategies].[无精子症所致不育症。病因、检查方法及治疗策略]
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