Korovin S I
Lik Sprava. 1998 May(3):114-7.
Results are analyzed of employment of different methods of adjuvant chemotherapy in patients with melanoma of the skin of the extremities and trunk. The courses of systemic prophylactic chemotherapy failed to improve results of surgical treatment of primary circumscribed melanoma of the skin. Adjuvant systemic chemotherapy and the immunomodulating agent levomizole combined in treatment of the condition did not change indices for late results of the treatment. The postoperative endolymphatic chemotherapy appeared to be associated with statistically significant (11.4%) increase in indices for a 5-year survival of patients with melanoma of the skin of the extremities and trunk.
对采用不同辅助化疗方法治疗四肢及躯干皮肤黑色素瘤患者的结果进行了分析。全身性预防性化疗疗程未能改善原发性局限性皮肤黑色素瘤的手术治疗效果。辅助性全身化疗与免疫调节剂左旋咪唑联合治疗该疾病并未改变治疗的远期结果指标。术后经淋巴管化疗似乎与四肢及躯干皮肤黑色素瘤患者5年生存率指标有统计学意义的提高(11.4%)相关。