• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Liquid chromatographic study of acid stability of 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, 2-chloro-2'-deoxyadenosine and related analogues.

作者信息

Reichelova V, Liliemark J, Albertioni F

机构信息

Department of Clinical Pharmacology, Karolinska Hospital, Stockholm, Sweden.

出版信息

J Pharm Biomed Anal. 1995 Apr;13(4-5):711-4. doi: 10.1016/0731-7085(95)01325-f.

DOI:10.1016/0731-7085(95)01325-f
PMID:9696594
Abstract
摘要

相似文献

1
Liquid chromatographic study of acid stability of 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, 2-chloro-2'-deoxyadenosine and related analogues.
J Pharm Biomed Anal. 1995 Apr;13(4-5):711-4. doi: 10.1016/0731-7085(95)01325-f.
2
Stability and analysis of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine and 2-chloroadenine in human blood plasma.
Anticancer Drugs. 1997 Jun;8(5):445-53. doi: 10.1097/00001813-199706000-00005.
3
Determination and quantification of intracellular fludarabine triphosphate, cladribine triphosphate and clofarabine triphosphate by LC-MS/MS in human cancer cells.采用液相色谱-串联质谱法(LC-MS/MS)测定和定量人癌细胞内的三磷酸氟达拉滨、三磷酸克拉屈滨和三磷酸氯法拉滨。
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 May 15;1053:101-110. doi: 10.1016/j.jchromb.2017.03.024. Epub 2017 Mar 24.
4
Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.对克拉屈滨和氯法拉滨耐药的人白血病细胞系中脱氧胞苷激酶的下调以及核糖核苷酸还原酶活性的增加导致了氟达拉滨耐药。
Biochem Pharmacol. 2003 Jan 15;65(2):237-47. doi: 10.1016/s0006-2952(02)01484-3.
5
Distribution of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, fludarabine and cytarabine in mice: a whole-body autoradiography study.
Med Oncol. 1999 Dec;16(4):239-44. doi: 10.1007/BF02785869.
6
Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.2-氯-2'-阿拉伯糖基氟-2'-脱氧腺苷(氯法拉滨)与克拉屈滨对急性髓性白血病和慢性淋巴细胞白血病患者单核细胞细胞毒性的比较
Haematologica. 2003 Mar;88(3):324-32.
7
Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.
Eur J Drug Metab Pharmacokinet. 1995 Jul-Sep;20(3):225-32. doi: 10.1007/BF03189674.
8
Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells.CCRF-CEM敏感细胞以及对克拉屈滨(CdA)和2-氯-2'-阿拉伯氟-2'-脱氧腺苷(CAFdA)耐药细胞中脱氧胞苷激酶基因5'区域的DNA甲基化分析。
Cancer Lett. 1998 Aug 14;130(1-2):169-73. doi: 10.1016/s0304-3835(98)00131-1.
9
Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.生化药理学与人类白血病细胞对2-氯-2'-阿拉伯糖基氟-2'-脱氧腺苷(一种新型克拉屈滨类似物)的耐药性
Clin Cancer Res. 1999 Sep;5(9):2438-44.
10
Clofarabine (2-chloro-2'-fluoro-2'-deoxyarabinosyladenine)--biochemical aspects of anticancer activity.氯法拉滨(2-氯-2'-氟-2'-脱氧阿拉伯糖基腺嘌呤)——抗癌活性的生化方面
Acta Pol Pharm. 2011 Jul-Aug;68(4):459-66.

引用本文的文献

1
Cladribine repurposed in multiple sclerosis: making a fortune out of a generic drug.用于多发性硬化症的克拉屈滨:从一种仿制药中获利。
Eur J Hosp Pharm. 2019 Sep;26(5):246-247. doi: 10.1136/ejhpharm-2019-002026. Epub 2019 Aug 30.
2
Phase I study of oral clofarabine consolidation in adults aged 60 and older with acute myeloid leukemia.口服氯法拉滨巩固治疗 60 岁及以上成人急性髓系白血病的 I 期研究。
Am J Hematol. 2014 May;89(5):487-92. doi: 10.1002/ajh.23663. Epub 2014 Mar 3.
3
Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases.
新旧嘌呤核苷类似物在淋巴增生性疾病治疗中的现状
Molecules. 2009 Mar 23;14(3):1183-226. doi: 10.3390/molecules14031183.
4
Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.
Eur J Drug Metab Pharmacokinet. 1995 Jul-Sep;20(3):225-32. doi: 10.1007/BF03189674.