Jaworkowsky L, Press B, Puschkarew I, Blumberg I
Z Gesamte Inn Med. 1976 Jan 1;31(1):302-4 contd.
In the first phase of inhalation due to the sedimentation of droplets against the walls of the atomizer arises a high loss of fluid in the apparatus. When the air flow was regular a high scattering volume of the consumed fluid quantity from the remedy store container was obtained. In the short-time inhalation this method cannot be used for the estimation of the quantity of medicaments applied to the patient. An exact dosage is possible only by measuring the fog flow and when the exact density of fog is known. When the presuppositions mentioned are not given, the informations about the virtual density of fog which was calculated by means of the analysis of regression, may be obtained.
在吸入的第一阶段,由于液滴沉积在雾化器壁上,设备中会出现大量液体损失。当气流规律时,从药物储存容器中消耗的液体量会有很高的散射量。在短时间吸入中,这种方法不能用于估计给予患者的药物量。只有通过测量雾流并已知雾的精确密度时,才可能实现精确给药。当未满足上述前提条件时,可以获得通过回归分析计算得出的关于雾的虚拟密度的信息。